Place of Origin: | China |
Brand Name: | Diacegene |
Certification: | CE |
Model Number: | β-HCG |
Minimum Order Quantity: | 1000 |
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Packaging Details: | 25test/carton |
Delivery Time: | 10~15 work days |
Payment Terms: | L/C, T/T |
Supply Ability: | 10,000 pcs/week |
Test Range: | 2.0~200000 MIU/mL | Valid Period: | 15 Months |
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Reaction Time: | 4~12 Minutes | Package: | 25 Tests |
Storage: | 2~8°C | Sample Type: | Serum/Plasma/Whole Blood |
Methodology: | Immunofluorescence | CV: | ≤10% |
High Light: | Beta-HCG Hormone Test Kits,2.0mIU/mL Hormone Test Kits |
Rapid Reaction for the Health of your next generation with Hormone β-HCG Test Kit
Serum HCG Levels During Pregnancy
Gestational weeks | HCG(IU/L |
0.2~1 | 5-50 |
1~2 | 50~500 |
2~3 | 100~5000 |
3~4 | 500~10000 |
4~5 | 1000~50000 |
5-6 | 10000-100000 |
6-8 | 15000-200000 |
2~3 months | 1 0000~100000 |
Although prior work has attempted to predict pregnancy outcomes by assaying serum β-hCG levels after blastocyst transfer, no study has focused on pregnancy outcomes in those with initially low serum β-hCG levels. This study sought to investigate pregnancy outcomes of patients with low serum β-hCG levels 14 days after blastocyst transfer.
A retrospective study was conducted at the Third Affiliated Hospital of Guangzhou Medical University to study patients whose serum β-hCG levels were at 5–299 mIU/ml 14 days after frozen blastocyst transfer. Rates of live birth, early miscarriage, biochemical pregnancy loss and ectopic pregnancy were analyzed according to the female patients’ age by Chi-squared analysis. Receiver operating characteristic (ROC) curves were plotted to explore the threshold of predicting clinical pregnancy and live births.
312 patients had serum β-hCG levels < 300 mIU/ml at 14 days after frozen blastocyst transfer, among which, 18.6% were live births, 47.4% were early miscarriages, 22.8% were biochemical pregnancies and 9.6% were ectopic pregnancies. ROC curve analysis showed that a predicted value of β-hCG for clinical pregnancy was 58.8 mIU/ml with an area under the ROC curve (AUC) of 0.752, a sensitivity of 95.0% and specificity of 53.5%. The threshold for live births was 108.6 mIU/ml with an AUC of 0.649, a sensitivity of 93.1% and a specificity of 37.0%. For the β-hCG fold increase over 48 h, the cut-off for clinical pregnancy was 1.4 with an AUC of 0.899, a sensitivity of 90.3% and a specificity of 77.8%. The threshold for live birth was 1.9 with an AUC of 0.808, a sensitivity of 88.5% and specificity of 64.5%.
Initially low serum β-hCG levels 14 days after frozen blastocyst transfer indicated minimal chances of live birth. For patients having an initial β-hCG > 58.8 mIU/ml, luteal phase support should continue. Another serum β-hCG test and ultrasound should be performed one week later. When an initial serum β-hCG is < 58.8 mIU/ml, luteal phase support should be discontinued and serum β-hCG measured with ultrasound one week later.
Contact Person: Eric King
Tel: +8613612761334
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